Resources
Publications & Reports
1- World Malaria Report 2017 -Read More
2- Evaluating Human Immune Responses for Vaccine Development in a Novel Human Spleen Cell-Engrafted NOD-SCID-IL2rgNull Mouse Model
Ghosn S, Chamat S, Prieur E, Stephan A, Druilhe P, Bouharoun-Tayoun H (2018) / Front. Immunol. 9:601. toi:10.3389/immu.2018.00601- Read More
3- Pre-Clinical Assessment of Novel Multivalent MSP3 Malaria Vaccine Constructs
Bang G, Prieur E, Roussillon C, Druilhe P (2011) / PlOS ONE 6(12):e28165. dos:1371/journal.pone.0028165 - Read More
4- Further Improvements of the P.falciparum Huamniazed Mouse Model
Arnold L, Tyagi RK, Meija P, Swetman C, Gleeson J et al. (2011) / PLoS ONE 6(3):e18045. dos:10.1371/journal.pone.0018045 - Read More
5- Interferon-g, a valuable surrogate marker of Plasmodium falciparum pre-erythrocytic stages protective immunity
Perlaza BL, Sauzet JP, Brahimi K, BenMohamed L, Druilhe P et al. / Malaria Journal 2011, 10:27 - Read More
6- Review - Immunity to liver stages
Druilhe P, Renia L, Fidock DA. - Read More
7- Understanding Human-Plasmodium falciparum Immune Interactions Uncovers the Immunological Role of Worms
Roussillon C, Brasseur P, Agnamey P, Perignon JL, Druilhe P. (2010) / PLoS ONE 5(2):e9309. dos:10.1371/journal.pone.0009309 -Read More
8- Toward the Rational Design of a Malaria Vaccine Construct Using the MSP3 Family as an Example: Contribution of Immunogenicity Studies in Models
Daher LJ, Demanga CG, Prieur E, Perignon JL, Bouharoun-Tayoun H, Druilhe D. / Infection and Immunity, 2010 Jan;78(1):477–485.- Read More
9- The relationship between anti-merozoite antibodies and incidence of Plasmodium falciparum malaria: A systematic review and meta-analysis.
Fowkes FJI, Richards JS, Simpson JA, Beeson JG (2010). / PLoS Med 7(1):e1000218. doi:10.1371/journal.pmed.1000218 -Read More
10- A Distinct Peripheral Blood Monocyte Phenotype Is Associated with Parasite Inhibitory Activity in Acute Uncomplicated Plasmodium falciparum Malaria - Chimma P, Roussilhon C, Sratongno P, Ruangveerayuth R, Pattanapanyasat K et al. (2009) / PLoS Pathog 5(10): e1000631. doi:10.1371/journal. ppat.1000631
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11- Safety and Immunogenicity of the Malaria Vaccine Candidate MSP3 Long Synthetic Peptide in 12–24 Months-Old Burkinabe Children
Sirima SB, Tiono AB, Ouedraogo A, Diarra A, Ouedraogo AL, et al. (2009) / PLoS ONE 4(10): e7549. doi:10.1371/journal.pone.0007549- Read More
12- The malaria candidate vaccine liver stage antigen-3 is highly conserved in Plasmodium falciparum isolates from diverse geographical areas
13- Satisfactory safety and immunogenicity of MSP3 malaria vaccine candidate in Tanzanian children aged 12–24 months
Lusingu JPA, Gesase S, Msham S, Francis F, Lemnge M et al. / Malaria Journal 2009, 8:163 - Read More
14- A Conserved Multi-Gene Family Induces Cross-Reactive Antibodies Effective in Defense against Plasmodium falciparum
Singh S, Soe S, Weisman S, Barnwell JW, Perignon JL, et al. (2009) / PLoS ONE 4(4): e5410. doi:10.1371/journal.pone.0005410 - Read More
15- Anti–MSP1 Block 2 Antibodies Are Effective at Parasite Killing in an Allele- Specific Manner by Monocyte-Mediated Antibody-Dependent Cellular Inhibition
16- Evidence for Multiple B- and T-Cell Epitopes in Plasmodium falciparum Liver-Stage Antigen 3
Toure-Balda A, Perlaza BL, Sauzet JP, Ndiaye M, Aribot G et al. / Infection and Immunity, 2009 Mar;77(3):1189-1196 - Read More
17- Genetic Immunisation by Liver Stage Antigen 3 Protects Chimpanzees against Malaria despite Low Immune Responses
Daubersies P, Ollomo B, Sauzet JP, Brahimi K, Perlaza BL et al. (2008) / PLoS ONE 3(7): e2659. doi:10.1371/journal.pone.0002659 - Read More
18- Protection against Plasmodium falciparum challenge induced in Aotus monkeys by liver-stage antigen-3- derived long synthetic peptides
Perlaza BL, Valencia AZ, Zapata C, Castellanos A, Sauzet JP et al. / Eur. J. Immunol. 2008. 38: 2610–2615 - Read More
19- Long-Term Clinical Protection from Falciparum Malaria Is Strongly Associated with IgG3 Antibodies to Merozoite Surface Protein
Roussilhon C, Oeuvray C, Muller-Graf C, Tall A, Rogier C, Trape JF, et al. / PLoS Med 2007;4:e320. - Read More
20- Pre-erythrocytic stage malaria vaccines: time for a change in path
21- Rapid Identification of Malaria Vaccine Candidates Based on a-Helical Coiled Coil Protein Motif
Villard V, Agak GW, Frank G, Jafarshad A, Servis C, et al (2007) / Coil Protein Motif. PLoS ONE 2(7): e645. doi:10.1371/journal.pone.0000645- Read More
22- Naturally acquired antibodies to polymorphic and conserved epitopes of Plasmodium falciparum merozoite surface protein 3
Osier FH, Polley SD, Mwangi T, Lowe B, Conway DJ, K. Marsh / Parasite Immunology 2007 ;29: 387–394 -Read More
23- A Novel Antibody-Dependent Cellular Cytotoxicity Mechanism Involved in Defense against Malaria Requires Costimulation of Monocytes Fc_RII and Fc_RIII
Jafarshad A, Dziegiel MH, Lundquist R, Nielsen LK, Singh S, Druilhe P. / The Journal Of Immunology, 2007 - Read More
24- Human Recombinant Antibodies against Plasmodium falciparum Merozoite Surface Protein 3 Cloned from Peripheral Blood Leukocytes of Individuals with Immunity to Malaria Demonstrate Antiparasitic Properties
Lundquist R, Nielsen LK, Jafarshad A, SoeSoe D, Christensen LH et al. / Infection and Immunity, 2006 June;74(6):3222-3231.- Read More
25- Liver-Stage Development of Plasmodium falciparum, in a Humanized Mouse Model
Morosan S, Hez-Deroubaix S, Lunel F, Renia L, Giannini C et al. / The Journal of Infectious Diseases 2006; 193:996–1004 - Read More
26- Antibody Responses to Several Malaria Pre-Erythrocytic Antigens as aa Marker of Malaria Exposure among Travelers
Orlandi-Pradines E, Penhoat K, Durand C, Pons C, Bay C et al. / Am. J. Trop. Med. Hyg., 74(6), 2006, pp. 979–985- Read More
27- Phase I Malaria Vaccine Trial with a Long Synthetic Peptide Derived from the Merozoite Surface Protein 3 Antigen
Audran R, Cachet M, Lurati F, Soe S, Leroy O et al. / Infection and Immunity, 2005 Dec;73(12):8017–8026. - Read More
28- A malaria vaccine that elicits in humans antibodies able to kill Plasmodium falciparum. PLoS Med
Druilhe P, Spertini F, Soesoe D, Corradin G, Mejia P, et al. (2005) / PLoS Med 2(11):e344. - Read More
29- Worms can worsen malaria: towards a new means to roll back malaria?
30- Insights into the P. y. yoelii hepatic stage transcriptome reveal complex transcriptional patterns
Grüner AC, Hez-Deroubaix S, Snounou G, Hall N, Bouchier C et al. / Molecular & Biochemical Parasitology 142 (2005) 184–192- Read More
31- Plasmodium falciparum Merozoite Surface Protein 6 Displays Multiple Targets for Naturally Occurring Antibodies That Mediate Monocyte-Dependent Parasite Killing
Singh S, Soe S, Roussilhon C, Corradin G, Druilhe P. / Infection and Immunity, 2005 Feb;73(2):1235-1238- Read More
32- Identification of a conserved region of Plasmodium falciparum MSP3 targeted by biologically active antibodies to improve vaccine design
Singh, S, Soe S, Mejia JP, Roussilhon C, Theisen M, Corradin G, et al. / J Infect Dis. 2004 Sep 1;190(5):1010-8 - Read More
33- Long-Term Multiepitopic Cytotoxic-T-Lymphocyte Responses Induced in Chimpanzees by Combinations of Plasmodium falciparum Liver-Stage Peptides and Lipopeptides
34- Increase of malaria attacks among children presenting concomitant infection by Schistosoma mansoni in Senegal
35- Effect on antibody and T-cell responses of mixing five GMP-produced DNA plasmids and administration with plasmid expressing GM-CSF
Sedegah M, Charoenvit Y, Aguiar J, Saci J, Hedstrom R et al. / Genes and Immunity (2004) 5, 553–561. doi:10.1038/sj.gene.6364125 - Read More
36- Association between protection against clinical malaria and antibodies to merozoite surface antigens in an area of hyperendemicity in Myanmar: complementarity between responses to merozoite surface protein 3 and the 220-kilodalton glutamaterich protein.
Soe S, Theisen M, Roussilhon C, Aye KS, Druilhe P. / Infection and Immunity 2004 Jan; 72(1):247-52. - Read More
37- A Plasmodium falciparum GLURP–MSP3 chimeric protein; expression in Lactococcus lactis, immunogenicity and induction of biologically active antibodies
Theisen M, Soe S, Brunstedt K, Follmann F, Bredmose L, et al. / Vaccine 22 (2004):1188-1198- Read More
38- Immunogenicity and protective efficacy of Plasmodium falciparum liver-stage Ag-3 in Aotus lemurinus griseimembra monkeys
Perlaza BL, Zapata C, Valencia AZ, Hurtado S, Quintero G et al. / Eur. J. Immunol. 2003. 33: 1321–1327- Read More
39- Pre-erythrocytic antigens of Plasmodium falciparum: from rags to riches?
Gruner AC, Snounou G, Brahimi K, Letourneur F, Renia L, Druilhe P. / TRENDS in Parasitology. 2003 Feb;19(2) - Read More
40- Analysis of intra-hepatic peptide-specific cell recruitment in mice immunised with Plasmodium falciparum antigens
Hebert A, Sauzet JP, Lebastard M, Ungeheuer MN, Ave P et al. / Journal of Immunological Methods 275 (2003) 123–132- Read More
41- Increased frequency of malaria attacks in subjects co-infected by intestinal worms and Plasmodium falciparum malaria
Spiegel A, Tall A, Raphenon G, Trape JF, Druilhe P. / Transactions of The Royal Society of Tropical Medicine and Hygiene (2003) 97, 198 - 199 - Read More
42- Plasmodium falciparum Serine Repeat Protein, a New Target of Monocyte-Dependent Antibody-Mediated Parasite Killing
Soe S, Singh S, Camus D, Horii T, Druilhe P. / Infection and Immunity, 2002 Dec;70(12):7182–7184 - Read More
43- Antibody-Dependent Cellular Inhibition Assay
Druilhe P, Bouharoun-Tayoun H. / Methods in Molecular Medicine, Vol. 72: Malaria Methods and Protocols / Edited by: Denise L. Doolan / 2002 - Read More
44- Systemic immune responses induced by mucosal administration of lipopeptides without adjuvant
BenMohammed L, Belkaid Y, Loing E, Brahimi K, Gras-Masse H, Druilhe P. / Eur. J. Immunol. 2002. 32: 2274–2281 - Read More
45- The importance of models of infection in the study of disease resistance
46- Expression of the Erythrocyte-Binding Antigen 175 in Sporozoites and in Liver Stages of Plasmodium falciparum
Gruner AC, Brahimi K, Letourneur F, Renia L et al. / The Journal of Infectious Diseases 2001;184:892–7 - Read More
47- Human Antibodies against Plasmodium falciparum Liver-Stage Antigen 3 Cross-React with Plasmodium yoelii Preerythrocytic-Stage Epitopes and Inhibit Sporozoite Invasion In Vitro and In Vivo
Brahimi K, Badell E, Sauzet JP, BenMohammed L, Daubersies P et al. / Infection and Immunity. 2001 June; 69(6):3845-3852 - Read More
48- DNA Immunization by Plasmodium falciparum Liver-Stage Antigen 3 Induces Protection against Plasmodium yoelii Sporozoite Challenge
Sauzet JP, Perlaza BL, Brahimi K, Daubersies P, Druilhe P. / Infection and Immunity, 2001 Feb;69(2):1202-1206 - Read More
49- The Plasmodium falciparum knob-associated PfEMP3 antigen is also expressed at pre-erythrocytic stages and induces antibodies which inhibit sporozoite invasion
Gruner AC, Brahimi K, Eling W, Konings R, Meis J et al. / Molecular & Biochemical Parasitology. 2001; 112:253-261 - Read More
50- Long synthetic peptides encompassing the Plasmodium falciparum LSA3 are the target of human B and T cells and are potent inducers of B helper, T helper and cytolytic T cell responses in mice
Perlaza BL, Sauzet JP, Toure Balde A, Brahimi K et al. / Eur. J. Immunol. 2001. 31:2200-2209 - Read More
51- Identification of a major B-cell epitope of the Plasmodium falciparum glutamate-rich protein (GLURP), targeted by human antibodies mediating parasite killing
Theisen M, Soe S, Jessing SG, Okkels LM, Danielsen S et al. / Vaccine 19 (2001) 2014-212 - Read More
52- Human Malaria in Immunocompromised Mice: An In Vivo Model to Study Defense Mechanisms against Plasmodium falciparum
Badell E, Oeuvray C, Moreno A, Soe S, Van Rooijen N, Bouzidi A, Druilhe P. / Brief Definitive Report, J. Exp. Med, 2000 Dec, 4;192(11):1653-1659. - Read More
53- Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liver-stage antigen 3
Daubersies P, Thomas AW, Millet P, Brahimi K, Langermans JA, Ollomo B, et al. / Nat Med 2000 Nov;6(11):1258-63- Read More
54- Cytotoxic T-Lymphocyte Epitopes for HLA-B53 and Other HLA Types in the Malaria Vaccine Candidate Liver-Stage Antigen 3
Aidoo M, Lalvani A, Gilbert SC, HU JT, Daubersies P et al. / Infection and Immunity, 2000 Jan;68(1):227-232 - Read More
55- High immunogenicity in chimpanzees of peptides and lipopeptides derived from four new Plasmodium falciparum pre-erythrocytic molecules
56- A Primary Malarial Infection Is Composed of a Very Wide Range of Genetically Diverse but Related Parasites
Druilhe P, Dauberies P, Patarapotikul J, Gentil C, Laurent Chene et al. / J. Clin. Invest. 1998 May; 101(9):2008-2016 - Read More
57- The Glutamate-Rich Protein (GLURP) of Plasmodium falciparum Is a Target for Antibody-Dependent Monocyte-Mediated Inhibition of Parasite Growth In Vitro
Theisen M, Soe Soe, Oeuvray C, Thomas AW, Vuust J, Danielsen S, Jepsen S, Druilhe P. / Infection and Immunity, 1998 Jan;66(1):11–17. - Read More
58- Immunogenicity of four Plasmodium falciparum pre-erythrocytic antigens in Aotus lemurinus monkeys
Perlaza LB, Arevalo-Herrera M, Brahimi K, Quintero G, Palomino JC et al./Infection and Immunity. 1998, 66(7):3423 - Read More
59- Plasmodium falciparum sporozoite invasion is inhibited by naturally acquired or experimentally induced polyclonal antibodies to the STARP antigen
Fidock DA, Pasquetto V, Gras H, Badell E, Eling W et al. / Eur J Immunol. 1997 Oct;27(10):2502-13. - Read More
60- A Hypothesis about the chronicity of Malaria Infection
61- HLA Class I-associated Resistance to Severe Malaria: A Parasitological Re-assessment
62- Lipopeptide immunization without adjuvant induces potent and long-lasting B, T helper, and cytotoxic T lymphocyte responses against a malaria liver stage antigen in mice and chimpanzees
BenMohammed L, Gras-Masse H, Tartar A, Daubersies P, Brahimi K et al. / Eur. J. Immunol. 1997. 27:1242-1253 - Read More
63- Plasmodium falciparum sporozoite invasion is inhibited by naturally acquired or experimentally induced polyclonal antibodies to the SIARP antige
Fidock DA, Pasquetto V, Gras H, Badell E, Eling W et al./ Eur. J. Immunol. 1997.27:2502-2513 - Read More
64- A Novel Plasmodium falciparum Sporozoite and liver Stage Antigen (SALSA) Defines Major B, T Helper, and CTL Epitopes
Bottius E, BenMohammed L, Brahimi K, Gras H, Lepers JP et al. / The Journal of Immunology, 1996 Feb; 156:2874-2884 - Read More
65- Mechanisms Underlying the Monocyte-mediated Antibody-dependent Killing of Plasmoclium falciparum Asexual Blood Stages
66- Antibody responses to Plasmodium falciparum sporozoite-, liver- and blood-stage synthetic peptides in migrant and autochthonous populations in malaria endemic areas
Ferreira-da-Cruz MF, Deslandes DC, Oliveira-Ferreira J, Montenegro-James S et al. /Parasite 1995 Mar;2(1):23-9. - Read More
67- Human PIasmodium Liver Stages in SCID Mice: A Feasible Model?
68- Conservation of the Plasmodium falciparum sporozoite surface protein gene, STARP, in field isolates and distinct species of Plasmodium
Fidock DA, Sallenave-Sales S, Sherwood JA, Gachihi GS et al. / Molecular and Biochemical Parasitology 1994;67:255-267 - Read More
69- Merozoite surface protein-3: a malaria protein inducing antibodies that promote Plasmodium falciparum killing by cooperation with blood monocytes
Oeuvray C, Bouharoun-Tayoun H, Gras-Masse H, Bottius E, Kaidoh T, Aikawa M, et al. / Blood 1994 Sept; 84(5):1594–1602 - Read More
70- Naturally Acquired Human Antibodies Which Recognize the First Epidermal Growth Factor-Like Module in the Plasmodium falciparum Merozoite Surface Protein 1 Do Not Inhibit Parasite Growth In Vitro
Chappel JA, Egan AF, Riley EM, Druilhe P, Holder AA. / Infection and Immunity, 1994 Oct;62(10):4488-4494- Read More
71- Plasmodium falciparum liver Stage Antigen-1 Is Well Conserved and Contains Potent B and T Cell Determinants
Fidock DA, Gras-Masse H, Jepers JP, Brahimi K, BenMohammed LB et al. / The Journal of Immunology, 1994, 153:190 - Read More
72- Cloning and characterization of a novel Plasmodium falciparum sporozoite surface antigen, STARP
Fidock DA, Bottius E, Brahimi K, Moellons IIMD, Aikawa M et al. / Molecular and Biochemical Parasitology, 1994;64:219-232- Read More
73- Antigenic analysis of Plasmodium yoelii liver stages by fluorescence antibody assays
Londono JA, Sedegah M, Charoenvit Y, Beaudoin RL, Druilhe P. / Trop. Med. Parasites. 1991 Dec; 42(4):381-385 - Read More
74- Plasmodium falciparum malaria: evidence for an isotype imbalance which may be responsible for delayed acquisition of protective immunity.
75- Parasitologic and clinical human response to immunoglobulin administration in falciparum malaria
Sabchareon A, Burnouf T, Ouattara D, Attanath P, Bouharoun-Tayoun H, Chantavanich P, et al. / Am. J. Trop. Med. Hyg. 1991;45(3):297–308.- Read More
76- Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro, but act in cooperation with monocytes
Bouharoun-Tayoun H, Attanath P, Sabchareon A, Chongsuphajaisiddhi T, Druilhe P. / J. Exp. Med. 1990 Dec;172:1633–1641. - Read More
77- Evidence for Diversity of Plasmodium falciparum Sporozoite Surface Antigens Derived from Analysis of Antibodies Elicited in Humans
Galey B, Druilhe P, Ploton I, Desgranges C, Asavanich A et al. / Infection and Immunity, 1990 Sept;58(9):2995-3001 - Read More
78- Secondary structure and immunogenicity of hybrid synthetic peptides derived from two Plasmodium falciparum pre-erythrocytic antigens
Londono JA, Gras-Masse H, Dubeaux C, Tartar A, Druilhe P. / The Journal of Immunology, 1990 Sept; 145(5):1557-1563 - Read More
79- Protection against malaria induced by irradiated sporozoites
Mellouk S Lunel F, Sedegah M, Beaudoin RL, Druilhe P. / Lancet. 1990 Mar 24;335(8691):721. - Read More
80- Impairment of Plasmodium falciparum-Specific Antibody Response in Severe Malaria
Brasseur P, Ballet JJ, Druilhe P. / Journal of Clinical Microbiology, 1990 Feb;28(2):265-268- Read More
81- Plasmodium falciparum: studies on Mature Exoerythrocytic Forms in the Liver of the Chimpanzee, Pan troglodytes
Meis JFGM, Ponnudurai T, Mons B, Belkum AV, Van Eerd PMCA, Druilhe P, Schellekens H. / Experimental Parasitology, 1990; 70:1-11 - Read More
82- Evaluation of an in vitro assay aimed at measuring protective antibodies against sporozoites
Mellouk S, Berbiguier N, Druilhe P, Sedegah M, Galey B et al. / Bulletin of the World Health Organization. 1990;68 (Suppl.): 52-59 - Read More
84- Effector Cells Involved in Nonspecific and Antibody-Dependent Mechanisms Directed against Plasmodium falciparum Blood Stages In Vitro
86- A liver-stage-specific antigen of Plasmodium falciparum characterized by gene cloning
Guerin-Marchand C, Druilhe P, Galey B, Londono A, Patarapotikul J et al. / Nature, 1987 Sept;329(6135):164-167 - Read More
87- Epidemiological Correlation between Levels of Antibodies Promoting Merozoite Phagocytosis of Plasmodium falciparum and Malaria-Immune Status
88- Levels of Antibodies to Plasrnodiumn falciparum Sporozoite Surface Antigens Reflect Malaria Transmission Rates and Are Persistent in the Absence of Reinfection
Druilhe P, Pradier O, Marc JP, Miltgen F, Mazier D, Parent G. / Infection and Immunity, 1986 Aug;53(2):393)397 - Read More
89- In Vitro and In Vivo results suggesting that anti-sporozoite antivodies do not totally block Plasmodium falciparum sporozoite infectivity
Mellouk S, Mazier D, Druilhe P, Berbiguier N, Danis M. / The New England Journal of Medicine, 1986 Sept Read More
90- Effect of Antibodies to Recombinant and Synthetc Peptides on P. falciparum Sporozoites in Vitro
91- Species and stage-specific antigens in exoerythrocytic stages of Plasmodium falciparum
Druilhe P, Puebla RM, Miltgen F, Perrin L, Gentilini M. / Am. J. Trop. Med. Hyg, 1984; 33(3):336-341 - Read More
92- Cultivation of the liver forms of Plasmodium vivax in human hepatocytes.
Mazier D, Landau I, Druilhe P, Miltgen F, Guguen-Guillouzo C et al. / Nature. 1984 Jan 26-Feb 1;307(5949):367-9. - Read More
94- Cooperation Between Antibodies and Monocytes that Inhibit In Vitro Proliferation of Plasmodium falciparum
95- In vitro infestation of human hepatocytes by sporozoites of Plasmodium vivax: schizogony and liberation of merozoites capable of infesting human erythrocytes
Mazier D, Landau I, Miltgen F, Druilhe P et al. / Ann Parasitol Hum Comp. 1983;58(4):405-6. - Read More
96- Exo-erythrocytic schizogony of plasmodium falciparum in the monkey Cebus apella
Druilhe P, Miltgen F, Landau I, Rinjard J, Gentilii M / C R Seances Acad Sci III. 1982 Mar 15;294(11):511-3. - Read More
97- Enhanced Plasmodium falciparum Merozoite Phagocytosis by Monocytes from Immune Individuals
98- Chimpanzees and supporting models in the study of malaria pre-erythrocytic stages
Thomas A, Slierendregt B, Mons B, Druilhe P. / Mem Inst Oswaldo Cruz, Rio de Janeiro. 1994;89 Suppl.II - Read More
99- From sporozoite to liver stages: the saga of the irradiated sporozoite vaccine
Druilhe P, Marchand C. - Read More
100- Natural Immunities
101- Evidence of protection against malaria by MSP3 candidate vaccine